Understanding the Microbiota Disruption in C-Section Births

This scientific summary examines a critical question in maternal and neonatal care: does the timing of antibiotic administration during C-section impact an infant's gut microbiota? Emerging evidence has long shown that babies born via cesarean section experience altered microbiota colonization, putting them at increased risk for immune and metabolic conditions, including respiratory infections and obesity. This resource focuses on findings from the MAMI study, which explores the microbiological effects of administering antibiotics either before skin incision or after cord clamping.

Key Learnings for Healthcare Professionals

As a healthcare professional, you will gain a concise yet impactful understanding of:

• How C-section delivery affects microbial colonization

• Why the timing of maternal antibiotic administration may not be the primary factor in microbiota disruption

• The implications of reduced Shannon diversity index and lower abundance of Bacteroides and Bifidobacteria

• Visual data comparing different delivery methods and antibiotic timings

These findings are essential to inform clinical decision-making around prophylactic antibiotic use and to guide early-life interventions that support a healthy microbiome in C-section-born infants.

Access the Full Educational Resource

View Content to access the full summary and explore the data behind this important topic. This infographic delivers clear, research-backed insights you can apply in your practice.