The EFFORT Protein and PRECISe trials on protein dosing for critically ill patients
Several Intensive Care experts, Prof. Arthur van Zanten, Prof. Elisabeth de Waele, Prof. Paul Wischmeyer, Prof. Christian Stoppe, and Dr. Marcel van de Poll provide an insightful session on the analysis of these 2 large clinical trials focused on protein dosing in mixed ICU populations. They further provide deeper insights from the EFFORT Protein and PRECISe trials, views on results interpretation and practical take outs for clinical practice.
These studies are among the first large-scale clinical trials look at protein dose not just for survival, but also for recovery and quality of life. The findings challenge traditional high protein dosing beliefs, advocating for personalized nutrition care.
Key takeaways include:
- Identifying patient groups who may benefit from higher protein targets.
- Aligning practices with current European guidelines, recommending 1.3g/kg/day protein as per ESPEN guidelines versus very high protein doses
- Good results and tolerance was achieved using the Nutrison high intact protein feeds, requiring < 5% protocol deviation and product switch.
- High protein enteral feeds, relative to calories are still required to enable patients to reach 1.3.g/kg/day protein intakes.
The session emphasizes practical application of trial data, providing healthcare professionals with tools to enhance patient outcomes, reduce risks, and confidently implement evidence-based, personalized nutrition strategies.
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The EFFORT Protein and PRECISe trials on protein dosing for critically ill patients
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