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Risk factors in the first 1000 days of life associated with childhood obesity: a systematic review and risk factor quality assessment

Adverse early life exposures might negatively affect foetal and infant development, predisposing children to obesity. In this paper, the researchers aimed to systematically identify and evaluate risk factors for childhood obesity in preconception, pregnancy, and infancy, and assess their potential as targets for future prediction and prevention strategies. This work was conducted by an expert group of the European branch of the International Life Sciences Institute, ILSI Europe.

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Risk factors in the first 1000 days of life associated with childhood obesity: a systematic review and risk factor quality assessment

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Portrait images of African gril baby newborn is 3-mount-old, lying and smile with happy on white bed, to African child and baby newborn concept.
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Risk factors in the first 1000 days of life associated with childhood obesity: a systematic review and risk factor quality assessment

Adverse early life exposures might negatively affect foetal and infant development, predisposing children to obesity. In this paper, the researchers aimed to systematically identify and evaluate risk factors for childhood obesity in preconception, pregnancy, and infancy, and assess their potential as targets for future prediction and prevention strategies. This work was conducted by an expert group of the European branch of the International Life Sciences Institute, ILSI Europe.

Portrait images of African gril baby newborn is 3-mount-old, lying and smile with happy on white bed, to African child and baby newborn concept.

This systematic review aimed to identify and evaluate early-life risk factors for childhood obesity from preconception through infancy. Analyzing 177 studies involving nearly 1.88 million children from 37 predominantly high-income countries, the review found a childhood obesity prevalence of 11.1%. The most commonly assessed age group was 2 to 6 years. Out of 59 potential risk factors, 24 were consistently linked to childhood obesity, including higher maternal prepregnancy weight, higher gestational weight gain, maternal smoking during pregnancy, higher birth weight, large for gestational age (LGA), lack of breastfeeding, and higher infant weight gain. The study noted that the quality of evidence was moderate due to issues like unreliable exposure measurement, short follow-up periods, and risk of confounding, underscoring the importance of addressing these risk factors in future prediction and prevention strategies for childhood obesity. 

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Risk factors in the first 1000 days of life associated with childhood obesity: a systematic review and risk factor quality assessment

Adverse early life exposures might negatively affect foetal and infant development, predisposing children to obesity. In this paper, the researchers aimed to systematically identify and evaluate risk factors for childhood obesity in preconception, pregnancy, and infancy, and assess their potential as targets for future prediction and prevention strategies. This work was conducted by an expert group of the European branch of the International Life Sciences Institute, ILSI Europe.

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Risk factors in the first 1000 days of life associated with childhood obesity: a systematic review and risk factor quality assessment

Adverse early life exposures might negatively affect foetal and infant development, predisposing children to obesity. In this paper, the researchers aimed to systematically identify and evaluate risk factors for childhood obesity in preconception, pregnancy, and infancy, and assess their potential as targets for future prediction and prevention strategies. This work was conducted by an expert group of the European branch of the International Life Sciences Institute, ILSI Europe.

Risk factors in the first 1000 days of life associated with childhood obesity: a systematic review and risk factor quality assessment

Adverse early life exposures might negatively affect foetal and infant development, predisposing children to obesity. In this paper, the researchers aimed to systematically identify and evaluate risk factors for childhood obesity in preconception, pregnancy, and infancy, and assess their potential as targets for future prediction and prevention strategies. This work was conducted by an expert group of the European branch of the International Life Sciences Institute, ILSI Europe.

Risk factors in the first 1000 days of life associated with childhood obesity: a systematic review and risk factor quality assessment

Adverse early life exposures might negatively affect foetal and infant development, predisposing children to obesity. In this paper, the researchers aimed to systematically identify and evaluate risk factors for childhood obesity in preconception, pregnancy, and infancy, and assess their potential as targets for future prediction and prevention strategies. This work was conducted by an expert group of the European branch of the International Life Sciences Institute, ILSI Europe.

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