Advancing Care for Infants with Refractory Epilepsy

The Ketogenic Diet Guidelines for Infants with Refractory Epilepsy present an evidence-based framework for using high-fat, low-carbohydrate nutrition as a therapeutic tool in challenging pediatric epilepsy cases. Developed by an international panel of pediatric neurologists and dietitians, the resource offers comprehensive protocols—from diagnosis and dietary initiation to monitoring and fine-tuning. It addresses specific epilepsy syndromes in infancy, outlines contraindications, and provides practical feeding strategies including use with breastmilk or formula.

Why This Resource Matters for Healthcare Professionals

By studying this guide you will:

• Gain practical, step-by-step protocols for initiating and managing the ketogenic diet in infants.

• Learn specific nutritional requirements for infants under 12 months, including protein, fluid, and micronutrient targets.

• Understand how to recognize and manage potential adverse effects such as hypoglycemia, gastrointestinal discomfort, or nutrient deficiencies.

• Access monitoring guidelines to track efficacy, tolerance, and growth over time.

• Explore tailored approaches for different epilepsy syndromes like West syndrome, Ohtahara syndrome, and GLUT-1 deficiency.

Take the Next Step in Your Clinical Practice

Review the guidelines on DNC to integrate the latest best practices into patient care. The full resource contains detailed tables, monitoring schedules, and clinical considerations that go beyond this summary.