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Critical Care Nutrition: Translating Trial Evidence into ICU Practice

Nutritional management in critically ill patients remains one of the most contested areas of clinical practice, with landmark randomised trials actively challenging long-held assumptions on protein dosing. Delayed or miscalibrated nutritional support contributes to muscle wasting, prolonged ventilation, and impaired functional recovery.

 

This hub brings together the latest randomised evidence on protein targets in the ICU, structured nutritional care pathways for high-risk patients, and first-hand patient insight on long-term enteral feeding, curated for critical care clinical practice.

 

patient-in-critical-care Hospital Ward: Portrait of Beautiful Young Woman Sleeping in Bed, Fully Recovering after Sickness. Female Patient Dreaming About Her Happy Healthy Future.

For years, higher protein intake in critically ill patients was assumed to improve survival. Recent large-scale randomised trial data challenge that assumption directly, showing that very high protein doses of around 2 g/kg/day do not improve mortality, physical function, or quality of life, and may be harmful in certain patient subgroups.

 

Moderate protein targets of 1.2 to 1.5 g/kg/day are now supported as more appropriate for most critically ill patients, with individualisation required based on condition, phase of illness, and renal replacement status. The evidence also points to functional recovery and quality of life, not mortality alone, as the clinically meaningful endpoints for ICU nutrition research.

 

>> WATCH THE WEBINAR FOR INSIGHTS ON PROTEIN DOSING AND PRACTICAL NUTRITION STRATEGIES IN CRITICALLY ILL ICU PATIENTS

patient-critical-care-nurse-doctor Emergency in the Hospital Doctor and Nurse Rush into the Ward to Safe Dying Patient. Man is Lying on the Bed without Signs of Life. Doctors Do Everything to Resuscitate Him.

patient-in-critical-care Hospital Coronavirus Emergency Department Ward: Doctor wearing Coverall Writes Down Vitals of a Senior Female Patient with Oxygen Mask Resting in Bed. Medics, Paramedics Doing everything to Save Lives

Older adults with fragility fractures are among the highest-risk groups for nutritional deterioration in acute care, yet unnecessary fasting and delayed nutritional support remain common in practice. Early nutritional risk identification and structured interdisciplinary pathways are key to reducing complications and supporting functional recovery in this population.

 

Real-world clinical cases illustrate how proactive, context-specific nutritional interventions, applied consistently across the care continuum, lead to measurable improvements in patient outcomes following hip and other fragility fractures.

 

>> WATCH THE VIDEO FOR INSIGHTS ON NUTRITION CARE PATHWAYS AND RECOVERY IN FRAGILITY FRACTURES

Enteral nutrition is a clinical intervention with significant day-to-day impact on patients' lives, yet that lived experience is rarely centred in clinical training. Understanding the practical and psychological challenges of long-term tube feeding informs more responsive, person-centred nutritional care decisions.

 

This video offers first-hand patient insight into living with tube feeding, providing a valuable perspective for clinicians managing enteral nutrition across critical care and rehabilitation settings.

 

>> WATCH THE VIDEO TO HEAR DIRECTLY FROM A PATIENT ON THE REALITIES OF TUBE FEEDING AND WHAT THAT MEANS FOR CLINICAL PRACTICE

ICU-patient Nurse fitting oxygen mask on patient in hospital bed. Man in intensive care unit in hospital.

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