Understanding HMOs in Human Milk

This publication investigates the presence and concentrations of Human Milk Oligosaccharides (HMOs), specifically Galactosyllactoses (GLs), in human milk according to maternal Secretor and Lewis (SeLe) phenotype and lactation stage. Through extensive analysis, researchers describe how specific HMOs such as 2′-fucosyllactose and sialyllactoses vary significantly depending on the mother's genetic profile and the infant's age. The findings provide healthcare professionals with insights into the dynamic nature of human milk composition.

Benefits for You as a Healthcare Professional

By reviewing this study, you will:

• Gain detailed knowledge about how maternal genetics (Secretor and Lewis phenotype) influences HMO profiles.

• Understand the variations in galactosyllactose (GL) concentrations, specifically β3′-GL and β6′-GL, across different lactation stages and maternal phenotypes.

• Explore the clinical implications of different HMO patterns, providing context for their potential roles in infant immune development, gut microbiota formation, and overall health.

Explore the Full Study

Click on "View Content" to access the detailed findings and explore how maternal phenotype and lactation stage influence HMO composition. Enhance your clinical understanding and learn more about these critical bioactive compounds, supporting evidence-based nutritional guidance for mothers and infants. 

This article is reused from: Eussen, S.R.B.M., Mank, M., Kottler, R., Hoffmann, X.-K., Behne, A., Rapp, E., Stahl, B., Mearin, M.L., Koletzko, B. Presence and Levels of Galactosyllactoses and Other Oligosaccharides in Human Milk and Their Variation during Lactation and According to Maternal Phenotype. Nutrients 2021, 13, 2324. No changes were made to the article.